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Deep two-photon brain imaging with a red-shifted fluorometric Ca(2+) indicator

In vivo Ca(2+) imaging of neuronal populations in deep cortical layers has remained a major challenge, as the recording depth of two-photon microscopy is limited because of the scattering and absorption of photons in brain tissue. A possible strategy to increase the imaging depth is the use of red-s...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tischbirek, Carsten, Birkner, Antje, Jia, Hongbo, Sakmann, Bert, Konnerth, Arthur
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568712/
https://ncbi.nlm.nih.gov/pubmed/26305966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514209112
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