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Protein folding guides disulfide bond formation

The Anfinsen principle that the protein sequence uniquely determines its structure is based on experiments on oxidative refolding of a protein with disulfide bonds. The problem of how protein folding drives disulfide bond formation is poorly understood. Here, we have solved this long-standing proble...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Qin, Meng, Wang, Wei, Thirumalai, D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568676/
https://ncbi.nlm.nih.gov/pubmed/26297249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503909112
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