Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression

Amino acid (aa) polymorphisms in the hepatitis C virus (HCV) genotype 1b core protein have been reported to be a potent predictor for poor response to interferon (IFN)-based therapy and a risk factor for hepatocarcinogenesis. We investigated the effects of these polymorphisms with genotype 1b/2a chi...

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Pubblicato in:Sci Rep
Autori principali: Tasaka-Fujita, Megumi, Sugiyama, Nao, Kang, Wonseok, Masaski, Takahiro, Murayama, Asako, Yamada, Norie, Sugiyama, Ryuichi, Tsukuda, Senko, Watashi, Koichi, Asahina, Yasuhiro, Sakamoto, Naoya, Wakita, Takaji, Shin, Eui-Cheol, Kato, Takanobu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568458/
https://ncbi.nlm.nih.gov/pubmed/26365522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13994
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