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Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment

Mitochondrial dysfunction represents a central factor within the pathogenesis of the Alzheimer's disease (AD) spectrum. We hypothesized that in vivo measurements of lactate (lac), a by-product of glycolysis, would correlate with functional impairment and measures of brain health in a cohort of...

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Pubblicato in:Biomed Res Int
Autori principali: Weaver, Kurt E., Richards, Todd L., Logsdon, Rebecca G., McGough, Ellen L., Minoshima, Satoshi, Aylward, Elizabeth H., Kleinhans, Natalia M., Grabowski, Thomas J., McCurry, Susan M., Teri, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568343/
https://ncbi.nlm.nih.gov/pubmed/26417597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/610605
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