IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

The series of events leading to tertiary lymphoid organ (TLO) formation in mucosal organs following tissue damage remain unclear. Using a virus-induced model of autoantibody formation in the salivary glands of adult mice, we demonstrate that IL-22 provides a mechanistic link between mucosal infectio...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Barone, Francesca, Nayar, Saba, Campos, Joana, Cloake, Thomas, Withers, David R., Toellner, Kai-Michael, Zhang, Yang, Fouser, Lynette, Fisher, Benjamin, Bowman, Simon, Rangel-Moreno, Javier, Garcia-Hernandez, Maria de la Luz, Randall, Troy D., Lucchesi, Davide, Bombardieri, Michele, Pitzalis, Costantino, Luther, Sanjiv A., Buckley, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568258/
https://ncbi.nlm.nih.gov/pubmed/26286991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503315112
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