Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3)

Toll-like receptors (TLRs) are crucial in innate recognition of invading micro-organisms and their subsequent clearance. Bacteria are not passive bystanders and have evolved complex evasion mechanisms. Staphylococcus aureus secretes a potent TLR2 antagonist, staphylococcal superantigen-like protein...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Koymans, Kirsten J., Feitsma, Louris J., Brondijk, T. Harma C., Aerts, Piet C., Lukkien, Eddie, Lössl, Philip, van Kessel, Kok P. M., de Haas, Carla J. C., van Strijp, Jos A. G., Huizinga, Eric G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568226/
https://ncbi.nlm.nih.gov/pubmed/26283364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502026112
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