Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3)

Toll-like receptors (TLRs) are crucial in innate recognition of invading micro-organisms and their subsequent clearance. Bacteria are not passive bystanders and have evolved complex evasion mechanisms. Staphylococcus aureus secretes a potent TLR2 antagonist, staphylococcal superantigen-like protein...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Koymans, Kirsten J., Feitsma, Louris J., Brondijk, T. Harma C., Aerts, Piet C., Lukkien, Eddie, Lössl, Philip, van Kessel, Kok P. M., de Haas, Carla J. C., van Strijp, Jos A. G., Huizinga, Eric G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568226/
https://ncbi.nlm.nih.gov/pubmed/26283364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502026112
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