Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome

Decitabine is a hypomethylating agent that irreversibly inhibits DNA methyltransferase I inducing leukemic differentiation and re-expression of epigenetically silenced putative tumor antigens. We assessed safety and efficacy of decitabine maintenance after allogeneic transplantation for acute myeloi...

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Detalhes bibliográficos
Publicado no:Biol Blood Marrow Transplant
Main Authors: Pusic, Iskra, Choi, Jaebok, Fiala, Mark A., Gao, Feng, Holt, Matthew, Cashen, Amanda F., Vij, Ravi, Abboud, Camille N., Stockerl-Goldstein, Keith E., Jacoby, Meghan A., Uy, Geoffrey L., Westervelt, Peter, DiPersio, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568135/
https://ncbi.nlm.nih.gov/pubmed/26055299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.05.026
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