T-bet and interleukin-27: possible T(H)1 immunomodulators of sarcoidosis

BACKGROUND: Sarcoidosis has often been termed an “immune paradox” as there is peripheral anergy to common recall antigens despite pronounced T(H)1-dominant inflammation at disease sites, such as the lung, with up-regulation of interferon γ, IL-27 and transcription factors. Peripheral blood may refle...

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Bibliografiske detaljer
Udgivet i:Inflammopharmacology
Main Authors: Loke, Wei Sheng Joshua, Freeman, Araluen, Garthwaite, Linda, Prazakova, Silvie, Park, Mijeong, Hsu, Kenneth, Thomas, Paul S., Herbert, Cristan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Basel 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568011/
https://ncbi.nlm.nih.gov/pubmed/26254778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10787-015-0247-y
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