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Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells

BACKGROUND: Genome-wide DNA methylation (DNAm) studies have proven extremely useful to understand human hematopoiesis. Due to their active DNA content, nucleated red blood cells (nRBCs) contribute to epigenetic and transcriptomic studies derived from whole cord blood. Genomic studies of cord blood h...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: de Goede, Olivia M., Razzaghian, Hamid R., Price, E. Magda, Jones, Meaghan J., Kobor, Michael S., Robinson, Wendy P., Lavoie, Pascal M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567832/
https://ncbi.nlm.nih.gov/pubmed/26366232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0129-6
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