Activation of Hepatic STAT3 Maintains Pulmonary Defense during Endotoxemia

Pneumonia and infection-induced sepsis are worldwide public health concerns. Both pathologies elicit systemic inflammation and induce a robust acute-phase response (APR). Although APR activation is well regarded as a hallmark of infection, the direct contributions of liver activation to pulmonary de...

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Udgivet i:Infect Immun
Main Authors: Hilliard, Kristie L., Allen, Eri, Traber, Katrina E., Kim, Yuri, Wasserman, Gregory A., Jones, Matthew R., Mizgerd, Joseph P., Quinton, Lee J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567648/
https://ncbi.nlm.nih.gov/pubmed/26216424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00464-15
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