Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D

Rhesus macaques were studied to directly address the potential for plasmid-deficient Chlamydia trachomatis to serve as a live attenuated vaccine in the genital tract. Five repeated cervical inoculations of rhesus macaques with wild-type serovar D strain D/UW-3/Cx or a plasmid-deficient derivative of...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Qu, Yanyan, Frazer, Lauren C., O'Connell, Catherine M., Tarantal, Alice F., Andrews, Charles W., O'Connor, Shelby L., Russell, Ali N., Sullivan, Jeanne E., Poston, Taylor B., Vallejo, Abbe N., Darville, Toni
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567646/
https://ncbi.nlm.nih.gov/pubmed/26216426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00841-15
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