Unexpected Roles for Toll-Like Receptor 4 and TRIF in Intraocular Infection with Gram-Positive Bacteria

Inflammation caused by infection with Gram-positive bacteria is typically initiated by interactions with Toll-like receptor 2 (TLR2). Endophthalmitis, an infection and inflammation of the posterior segment of the eye, can lead to vision loss when initiated by a virulent microbial pathogen. Endophtha...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Parkunan, Salai Madhumathi, Randall, C. Blake, Coburn, Phillip S., Astley, Roger A., Staats, Rachel L., Callegan, Michelle C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567632/
https://ncbi.nlm.nih.gov/pubmed/26195555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00502-15
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