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PATHOLOGICAL EFFECTS OF OBSTRUCTIVE APNEAS DURING THE SLEEP CYCLE IN AN ANIMAL MODEL OF CEREBRAL SMALL VESSEL DISEASE

We tested the hypothesis that apneas during the sleep cycle exacerbate hypertension and accelerate changes that occur with cerebral small vessel disease (CSVD). Obstructive sleep apnea was modeled by intermittent inflations of a tracheal balloon to occlude the airway during the sleep cycle (termed O...

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Détails bibliographiques
Publié dans:Hypertension
Auteurs principaux: Lloyd, Eric E., Durgan, David J., Martini, Sharyl R., Bryan, Robert M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567494/
https://ncbi.nlm.nih.gov/pubmed/26259594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05764
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