ABNORMAL REGULATION OF MICROVASCULAR TONE IN A MURINE MODEL OF SICKLE CELL DISEASE ASSESSED BY CONTRAST ULTRASOUND

BACKGROUND: Microvascular dysregulation, abnormal rheology, and vaso-occlusive events play a role in the pathophysiology of sickle cell disease (SCD). We hypothesized that abnormalities in skeletal muscle perfusion in a murine model of SCD could be parametrically assessed by quantitative contrast-en...

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Veröffentlicht in:J Am Soc Echocardiogr
Hauptverfasser: Wu, Melinda D., Belcik, J. Todd, Qi, Yue, Zhao, Yan, Benner, Cameron, Pei, Hong, Linden, Joel, Lindner, Jonathan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567487/
https://ncbi.nlm.nih.gov/pubmed/26123012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.echo.2015.05.012
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