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AN ALPHAVIRUS TEMPERATURE-SENSITIVE CAPSID MUTANT REVEALS STAGES OF NUCLEOCAPSID ASSEMBLY

Alphaviruses have a nucleocapsid core composed of the RNA genome surrounded by an icosahedral lattice of capsid protein. An insertion after position 186 in the capsid protein produced a strongly temperature-sensitive growth phenotype. Even when the structural proteins were synthesized at the permiss...

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書目詳細資料
發表在:Virology
Main Authors: Zheng, Yan, Kielian, Margaret
格式: Artigo
語言:Inglês
出版: 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567448/
https://ncbi.nlm.nih.gov/pubmed/26051211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.05.011
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