AT2R AUTOANTIBODIES BLOCK ANGIOTENSIN II AND AT1R AUTOANTIBODY-INDUCED VASOCONSTRICTION

Activating autoantibodies to the angiotensin type 1 receptor (AT1R) are associated with hypertensive disorders. The angiotensin type 2 receptor (AT2R) is known to counter-regulate the actions of AT1R. We investigated whether AT2R autoantibodies produced in immunized rabbits will activate AT2R and su...

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Dettagli Bibliografici
Pubblicato in:Hypertension
Autori principali: Liles, Campbell, Li, Hongliang, Veitla, Vineet, Liles, Jonathan T., Murphy, Taylor A., Cunningham, Madeleine W., Yu, Xichun, Kem, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567423/
https://ncbi.nlm.nih.gov/pubmed/26259590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05428
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