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PD-1 Blockade Can Restore Functions of T-Cells in Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma In Vitro

Epstein–Barr virus-positive diffuse large B-cell lymphoma (EBV+DLBCL) is an aggressive malignancy that is largely resistant to current therapeutic regimens, and is an attractive target for immune-based therapies. Anti-programmed death-1 (PD-1) antibodies showed encouraging anti-tumor effects in both...

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Publicado en:PLoS One
Autores principales: Quan, Lina, Chen, Xue, Liu, Aichun, Zhang, Yan, Guo, Xiuchen, Yan, Shujie, Liu, Yue
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567291/
https://ncbi.nlm.nih.gov/pubmed/26361042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136476
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