Age-Associated Differences in MiRNA Signatures Are Restricted to CD45RO Negative T Cells and Are Associated with Changes in the Cellular Composition, Activation and Cellular Ageing

MicroRNAs (miRNAs) have emerged as important players in the regulation of T-cell functionality. However, comprehensive insight into the extent of age-related miRNA changes in T cells is lacking. We established miRNA expression patterns of CD45RO- naïve and CD45RO+ memory T-cell subsets isolated from...

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Vydáno v:PLoS One
Hlavní autoři: Teteloshvili, Nato, Kluiver, Joost, van der Geest, Kornelis S. M., van der Lei, Roelof Jan, Jellema, Pytrick, Pawelec, Graham, Brouwer, Elisabeth, Kroesen, Bart-Jan, Boots, Annemieke M. H., van den Berg, Anke
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567287/
https://ncbi.nlm.nih.gov/pubmed/26360056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137556
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