Longitudinal Detection and Persistence of Minority Drug-Resistant Populations and Their Effect on Salvage Therapy

BACKGROUND: Drug-resistant HIV are more prevalent and persist longer than previously demonstrated by bulk sequencing due to the ability to detect low-frequency variants. To clarify a clinical benefit to monitoring minority-level drug resistance populations as a guide to select active drugs for salva...

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Udgivet i:PLoS One
Main Authors: Nishizawa, Masako, Matsuda, Masakazu, Hattori, Junko, Shiino, Teiichiro, Matano, Tetsuro, Heneine, Walid, Johnson, Jeffrey A., Sugiura, Wataru
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567277/
https://ncbi.nlm.nih.gov/pubmed/26360259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135941
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