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An open access microfluidic device for the study of the physical limits of cancer cell deformation during migration in confined environments

During metastasis, cancerous cells leave the primary tumour, pass into the circulatory system, and invade into new tissues. To migrate through the wide variety of environments they encounter, the cells must be able to remodel their cell shape efficiently to squeeze through small gaps in the extracel...

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Publicado en:Microelectron Eng
Autores principales: Malboubi, Majid, Jayo, Asier, Parsons, Maddy, Charras, Guillaume
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567073/
https://ncbi.nlm.nih.gov/pubmed/26412914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mee.2015.02.022
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