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Polar stimulation and constrained cell migration in microfluidic channels

Asymmetrical delivery of stimuli to moving cells for perturbing spatially-heterogeneous intracellular signaling is an experimental challenge not adequately met by existing technologies. Here, we report a robust microfluidic platform allowing localized treatment of the front and/or back of moving cel...

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Detalhes bibliográficos
Main Authors: Irimia, Daniel, Charras, Guillaume, Agrawal, Nitin, Mitchison, Timothy, Toner, Mehmet
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001245/
https://ncbi.nlm.nih.gov/pubmed/18030401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b710524j
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