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Karyopherin α 3 and Karyopherin α 4 Proteins Mediate the Nuclear Import of Methyl-CpG Binding Protein 2

Methyl-CpG binding protein 2 (MeCP2) is a nuclear protein with important roles in regulating chromatin structure and gene expression, and mutations in MECP2 cause Rett syndrome (RTT). Within the MeCP2 protein sequence, the nuclear localization signal (NLS) is reported to reside between amino acids 2...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Baker, Steven Andrew, Lombardi, Laura Marie, Zoghbi, Huda Yahya
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566224/
https://ncbi.nlm.nih.gov/pubmed/26245896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.658104
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