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Can kinomics and proteomics bridge the gap between pediatric cancers and newly designed kinase inhibitors?

The introduction of kinase inhibitors in cancer medicine has transformed chronic myeloid leukemia from a fatal disease into a leukemia subtype with a favorable prognosis by interfering with the constitutively active kinase BCR-ABL. This success story has resulted in the development of multiple kinas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Life Sci
Egile Nagusiak: van der Sligte, Naomi E., Kampen, Kim R., de Bont, Eveline S. J. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Basel 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565869/
https://ncbi.nlm.nih.gov/pubmed/26321002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2019-7
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