Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele

BACKGROUND: Arsenic induces neural tube defects in many animal models. Additionally, studies have shown that mice with specific genetic defects in folate metabolism and transport are more susceptible to arsenic-induced neural tube defects. We sought to determine whether 14 single-nucleotide polymorp...

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Publicado en:Birth Defects Res A Clin Mol Teratol
Autores principales: Mazumdar, Maitreyi, Valeri, Linda, Rodrigues, Ema G., Hasan, Md Omar Sharif Ibne, Hamid, Rezina, Paul, Ligi, Selhub, Jacob, Silva, Fareesa, Mostofa, MdGolam, Quamruzzaman, Quazi, Rahman, Mahmuder, Christiani, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565773/
https://ncbi.nlm.nih.gov/pubmed/26250961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23399
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