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Appraising the Role of Iron in Brain Aging and Cognition: Promises and Limitations of MRI Methods
Age-related increase in frailty is accompanied by a fundamental shift in cellular iron homeostasis. By promoting oxidative stress, the intracellular accumulation of non-heme iron outside of binding complexes contributes to chronic inflammation and interferes with normal brain metabolism. In the abse...
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| Publicat a: | Neuropsychol Rev |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565753/ https://ncbi.nlm.nih.gov/pubmed/26248580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11065-015-9292-y |
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