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Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity

The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine, testing of the safety and efficacy of the use of inactivated antigen plus adjuvant is needed. Here, we assessed various types of adjuvants in...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kim, Eun-Do, Han, Soo Jung, Byun, Young-Ho, Yoon, Sang Chul, Choi, Kyoung Sub, Seong, Baik Lin, Seo, Kyoung Yul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565664/
https://ncbi.nlm.nih.gov/pubmed/26355295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137608
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