The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation is under tight control, i.e. cells respond to a signal to proliferate, a...

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Pubblicato in:Carcinogenesis
Autori principali: Engström, Wilhelm, Darbre, Philippa, Eriksson, Staffan, Gulliver, Linda, Hultman, Tove, Karamouzis, Michalis V., Klaunig, James E., Mehta, Rekha, Moorwood, Kim, Sanderson, Thomas, Sone, Hideko, Vadgama, Pankaj, Wagemaker, Gerard, Ward, Andrew, Singh, Neetu, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Colacci, Anna Maria, Vaccari, Monica, Mondello, Chiara, Scovassi, A. Ivana, Raju, Jayadev, Hamid, Roslida A., Memeo, Lorenzo, Forte, Stefano, Roy, Rabindra, Woodrick, Jordan, Salem, Hosni K., Ryan, Elizabeth, Brown, Dustin G., Bisson, William H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565610/
https://ncbi.nlm.nih.gov/pubmed/26106143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv030
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