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Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach

AIMS: Diseases that abbreviate the cardiac action potential (AP) by increasing the strength of repolarizing transmembrane currents are highly arrhythmogenic. It has been proposed that optogenetic tools could be used to restore normal AP duration (APD) in the heart under such disease conditions. This...

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Pubblicato in:Europace
Autori principali: Karathanos, Thomas V., Boyle, Patrick M., Trayanova, Natalia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565556/
https://ncbi.nlm.nih.gov/pubmed/25362173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/europace/euu250
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