CYP2J2 Overexpression Ameliorates Hyperlipidemia via Increased Fatty Acid Oxidation Mediated by the AMPK Pathway

OBJECTIVE: The study aims to investigate the effect of Cytochrome P450 2J2 (CYP2J2) overexpression on hyperlipidemia in mice and further to explore their effect on fatty acid oxidation in vivo and in vitro. METHODS: The effects and mechanisms of endothelial-specific CYP2J2 transgene (Tie2-CYP2J2-Tr)...

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Vydáno v:Obesity (Silver Spring)
Hlavní autoři: Zhang, Shasha, Chen, Guangzhi, Li, Ning, Dai, Meiyan, Chen, Chen, Wang, Peihua, Tang, Huiru, Hoopes, Samantha L., Zeldin, Darryl C., Wang, Dao Wen, Xu, Xizhen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565055/
https://ncbi.nlm.nih.gov/pubmed/26053032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21115
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