Implementation of a Chronic Unilateral Intraparenchymal Drug Delivery System in a Swine Model

BACKGROUND: Systemic delivery of pharmacologic agents has led to many significant advances in the treatment of neurologic and psychiatric conditions. However, this approach has several limitations, including difficulty penetrating the blood-brain barrier and enzymatic degradation prior to reaching i...

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Bibliografiske detaljer
Udgivet i:J Neurosci Methods
Main Authors: Kim, Inyong, Paek, Seungleal, Nelson, Brian D., Knight, Emily J., Marsh, Michael P., Bieber, Allan J., Bennet, Kevin E., Lee, Kendall H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564994/
https://ncbi.nlm.nih.gov/pubmed/24486877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2014.01.029
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