Novel chemical scaffolds of the tumor marker AKR1B10 inhibitors discovered by 3D QSAR pharmacophore modeling

AIM: Recent evidence suggests that aldo-keto reductase family 1 B10 (AKR1B10) may be a potential diagnostic or prognostic marker of human tumors, and that AKR1B10 inhibitors offer a promising choice for treatment of many types of human cancers. The aim of this study was to identify novel chemical sc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Kumar, Raj, Son, Minky, Bavi, Rohit, Lee, Yuno, Park, Chanin, Arulalapperumal, Venkatesh, Cao, Guang Ping, Kim, Hyong-ha, Suh, Jung-keun, Kim, Yong-seong, Kwon, Yong Jung, Lee, Keun Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564875/
https://ncbi.nlm.nih.gov/pubmed/26051108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.17
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados