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Loss of G2 subunit of vacuolar-type proton transporting ATPase leads to G1 subunit upregulation in the brain

Vacuolar-type ATPase (V-ATPase) is a primary proton pump with versatile functions in various tissues. In nerve cells, V-ATPase is required for accumulation of neurotransmitters into secretory vesicles and subsequent release at the synapse. Neurons express a specific isoform (G2) of the G subunit of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawamura, Nobuyuki, Sun-Wada, Ge-Hong, Wada, Yoh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564858/
https://ncbi.nlm.nih.gov/pubmed/26353914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14027
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