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Rhein antagonizes P2X(7) receptor in rat peritoneal macrophages

P2X(7) receptor plays important roles in inflammation and immunity, and thereby it serves as a potential therapeutic target for inflammatory diseases. Rhein, an anthraquinone derivative, exhibits significant anti-inflammatory and immunosuppressive activities in therapy. However, the underlying mecha...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hu, Fen, Xing, Fulin, Zhu, Ge, Xu, Guangxue, Li, Cunbo, Qu, Junle, Lee, Imshik, Pan, Leiting
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564849/
https://ncbi.nlm.nih.gov/pubmed/26354875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14012
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