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Lentivirus-Mediated siRNA Targeting ER-α Inhibits Tumorigenesis and Induces Apoptosis in Hepatocarcinoma Cells

Background and Objectives. Estrogen receptor-α (ER-α) plays important roles in hepatocarcinogenesis. Recent studies have shown that ER-α could lead to cell cycle progression or inhibition of apoptosis. To better understand the role of ER-α, RNA interference (RNAi) was used to inhibit ER-α expression...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Jiang, Ping, Cao, Jun, Bai, Wen-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564599/
https://ncbi.nlm.nih.gov/pubmed/26413526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/490681
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