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Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin

Background. BST2/tetherin is an innate immune molecule with the unique ability to restrict the egress of human immunodeficiency virus (HIV) and other enveloped viruses, including Ebola virus (EBOV). Coincident with this discovery was the finding that the HIV Vpu protein down-regulates BST2 from the...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Gustin, Jean K., Bai, Ying, Moses, Ashlee V., Douglas, Janet L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564538/
https://ncbi.nlm.nih.gov/pubmed/25821226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv125
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