Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens

The assessment of individual risk of fibrosis progression in patients with chronic hepatitis C is an unmet clinical need. Recent genome-wide association studies have highlighted several genetic alterations as predictive risk factors of rapid fibrosis progression in chronic hepatitis C. However, most...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tamaki, Nobuharu, Kurosaki, Masayuki, Higuchi, Mayu, Takada, Hitomi, Nakakuki, Natsuko, Yasui, Yutaka, Suzuki, Shoko, Tsuchiya, Kaoru, Nakanishi, Hiroyuki, Itakura, Jun, Takahashi, Yuka, Ogawa, Shintaro, Tanaka, Yasuhito, Asahina, Yasuhiro, Izumi, Namiki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564246/
https://ncbi.nlm.nih.gov/pubmed/26352693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137351
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