SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells

Epibrassinolide (EBR) is a polyhydroxylated sterol derivative and biologically active compound of the brassinosteroids. In addition to well-described roles in plant growth, EBR induces apoptosis in the LNCaP prostate cancer cells expressing functional androgen receptor (AR). Therefore, it is suggest...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Obakan, Pinar, Barrero, Carlos, Coker-Gurkan, Ajda, Arisan, Elif Damla, Merali, Salim, Palavan-Unsal, Narcin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564160/
https://ncbi.nlm.nih.gov/pubmed/26353013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135788
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