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Brief Communication: Vogt-Koyanagi-Harada-like Syndrome Following CTLA-4 Inhibition with Ipilimumab for Metastatic Melanoma
Cytotoxic T-lymphocyte-associated antigen (CTLA-4) is a naturally occurring inhibitor of T-cell costimulation. Monoclonal antibody inhibition of CTLA-4 with ipilimumab blocks this negative regulator of costimulation, promoting T-cell activation and survival, and leads to melanoma regression. Finding...
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| Pubblicato in: | J Immunother |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564122/ https://ncbi.nlm.nih.gov/pubmed/25658618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000066 |
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