Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation

AMP-activated protein kinase (AMPK), a sensor of cellular energy, is widely reported as a potential therapeutic target in treatment of breast and other cancers. The activated enzyme has been shown to be a promising anti-proliferative agent in breast cancer cell lines. However, little data exist on c...

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Udgivet i:Oncol Rep
Main Authors: EL-MASRY, OMAR S., AL-SAKKAf, KALTOOM, BROWN, BARRY L., DOBSON, PAULINE R.M.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564084/
https://ncbi.nlm.nih.gov/pubmed/26260992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.4198
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