Deoxyinosine repair in nuclear extracts of human cells

BACKGROUND: Deamination of adenine can occur spontaneously under physiological conditions generating the highly mutagenic lesion, hypoxanthine. This process is enhanced by ROS from exposure of DNA to ionizing radiation, UV light, nitrous acid, or heat. Hypoxanthine in DNA can pair with cytosine whic...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Lee, Chia-Chia, Yang, Ya-Chien, Goodman, Steven D., Chen, Shi, Huang, Teng-Yung, Cheng, Wern-Cherng, Lin, Liang-In, Fang, Woei-horng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563847/
https://ncbi.nlm.nih.gov/pubmed/26357532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0044-8
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