The CB(1) cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway

The CB(1) cannabinoid receptor, the main molecular target of endocannabinoids and cannabis active components, is the most abundant G protein-coupled receptor in the mammalian brain. In particular, the CB(1) receptor is highly expressed in the basal ganglia, mostly on terminals of medium-sized spiny...

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Vydáno v:Cell Death Differ
Hlavní autoři: Blázquez, C, Chiarlone, A, Bellocchio, L, Resel, E, Pruunsild, P, García-Rincón, D, Sendtner, M, Timmusk, T, Lutz, B, Galve-Roperh, I, Guzmán, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563779/
https://ncbi.nlm.nih.gov/pubmed/25698444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.11
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