Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

Direct delivery of aerosolized vaccines to the respiratory mucosa elicits both systemic and mucosal responses. This vaccine strategy has not been tested for Ebola virus (EBOV) or other hemorrhagic fever viruses. Here, we examined the immunogenicity and protective efficacy of an aerosolized human par...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Meyer, Michelle, Garron, Tania, Lubaki, Ndongala M., Mire, Chad E., Fenton, Karla A., Klages, Curtis, Olinger, Gene G., Geisbert, Thomas W., Collins, Peter L., Bukreyev, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563760/
https://ncbi.nlm.nih.gov/pubmed/26168222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81532
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