Outcomes of acute leukemia patients transplanted with naive T cell–depleted stem cell grafts

BACKGROUND. Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HCT). In mice, naive T cells (T(N)) cause more severe GVHD than memory T cells (T(M)). We hypothesized that selective depletion of T(N) from human al...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Bleakley, Marie, Heimfeld, Shelly, Loeb, Keith R., Jones, Lori A., Chaney, Colette, Seropian, Stuart, Gooley, Ted A., Sommermeyer, Franziska, Riddell, Stanley R., Shlomchik, Warren D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2015
Ämnen:
Clinical Medicine
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563691/
https://ncbi.nlm.nih.gov/pubmed/26053664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81229
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