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Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1
Macrophages clear millions of apoptotic cells daily and, during this process, take up large quantities of cholesterol. The membrane transporter ABCA1 is a key player in cholesterol efflux from macrophages and has been shown via human genetic studies to provide protection against cardiovascular disea...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563683/ https://ncbi.nlm.nih.gov/pubmed/26075824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80300 |
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