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AB075. Mutations of WT1 gene caused 46,XY disorder of sex development and Wilms’ tumor
The Wilms’ tumor suppressor gene (WT1) is a transcription factor that plays a major role in development of the gonads and kidneys. It is expressed even earlier than sex-determining region of the Y chromosome in the urogenital ridge from which the gonads and kidneys are derived. WT1 mutations will im...
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| Publicado no: | Ann Transl Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563516/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2015.AB075 |
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