TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients

We investigated the hypothesis that the varying treatment efficacy of adjuvant 5-fluorouracil (5FU) in stage III colon cancer is linked to the TP53 mutational status. ABCSG-90 was a prospective randomized trial in which effect of adjuvant 5FU was studied in stage III colon cancer patients. Tumor mat...

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Publicado en:EBioMedicine
Main Authors: Kandioler, Daniela, Mittlböck, Martina, Kappel, Sonja, Puhalla, Harald, Herbst, Friedrich, Langner, Cord, Wolf, Brigitte, Tschmelitsch, Jörg, Schippinger, Walter, Steger, Günther, Hofbauer, Friedrich, Samonigg, Hellmut, Gnant, Michael, Teleky, Bela, Kührer, Irene
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563117/
https://ncbi.nlm.nih.gov/pubmed/26425688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.06.003
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