Pulmonary receptor for advanced glycation endproducts promotes asthma pathogenesis via IL-33 and accumulation of group 2 innate lymphoid cells

BACKGROUND: Single nucleotide polymorphisms in the human gene for the receptor for advanced glycation end products (RAGE) are associated with an increased incidence of asthma. RAGE is highly expressed in the lung and has been reported to play a vital role in the pathogenesis of murine models of asth...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Oczypok, Elizabeth A., Milutinovic, Pavle S., Alcorn, John F., Khare, Anupriya, Crum, Lauren T., Manni, Michelle L., Epperly, Michael W., Pawluk, Adriane M., Ray, Anuradha, Oury, Tim D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562894/
https://ncbi.nlm.nih.gov/pubmed/25930197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.03.011
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