Heritability of Telomere Length in a Study of Long-Lived Families

Chromosomal telomere length shortens with repeated cell divisions. Human leukocyte DNA telomere length (LTL) determined has been shown to shorten during aging. LTL shortening has correlated with decreased longevity, dementia, and other age-associated processes. Since LTL varies widely between indivi...

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Udgivet i:Neurobiol Aging
Main Authors: Honig, Lawrence S., Kang, Min Suk, Cheng, Rong, Eckfeldt, John H., Thyagarajan, Bharat, Leiendecker-Foster, Catherine, Province, Michael A., Sanders, Jason L., Perls, Thomas, Christensen, Kaare, Lee, Joseph H., Mayeux, Richard P., Schupf, Nicole
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562863/
https://ncbi.nlm.nih.gov/pubmed/26239175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.06.017
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