Recombinant H7 hemagglutinin forms subviral particles that protect mice and ferrets from challenge with H7N9 influenza virus

A novel avian-origin influenza A H7N9 virus emerged in China in 2013 and continues to cause sporadic human infections with mortality rates approaching 35%. Currently there are no approved human vaccines for H7N9 virus. Recombinant approaches including hemagglutinin (HA) and virus-like particles (VLP...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Pushko, Peter, Pujanauski, Lindsey M., Sun, Xiangjie, Pearce, Melissa, Hidajat, Rachmat, Kort, Thomas, Schwartzman, Louis M., Tretyakova, Irina, Chunqing, Liu, Taubenberger, Jeffery K., Tumpey, Terrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562812/
https://ncbi.nlm.nih.gov/pubmed/26207590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.07.026
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