Cytokine-dependent bidirectional connection between impaired social behavior and susceptibility to seizures associated with maternal immune activation in mice

Maternal immune activation (MIA) results in the development of autism in the offspring via hyperactivation of IL-6 signaling. Furthermore, experimental studies showed that the MIA-associated activation of interleukin-1β (IL-1β) concurrently with IL-6 increases the rate and the severity of hippocampa...

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Vydáno v:Epilepsy Behav
Hlavní autoři: Washington, James, Kumar, Udaya, Medel-Matus, Jesus-Servando, Shin, Don, Sankar, Raman, Mazarati, Andrey
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562803/
https://ncbi.nlm.nih.gov/pubmed/26103532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2015.05.040
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